THC, CBD, cannabinoids, psychoactive hopena - ua lohe paha ʻoe i ʻelua o kēia mau huaʻōlelo inā ʻoe e hoʻāʻo e hoʻomaopopo i ka THC, CBD, a me nā ʻokoʻa ma waena o lākou. Malia paha ua ʻike ʻoe i ka ʻōnaehana endocannabinoid, cannabinoid receptors, a me nā terpenes. Akā, he aha ia mea?
Inā ʻoe e ʻimi nei i kahi ala e hoʻomaopopo ai i ke kumu e kiʻekiʻe ai nā huahana THC iā ʻoe a ʻaʻole nā huahana CBD a me nā mea e pili ana i nā endocannabinoids, aloha, aia ʻoe ma kahi kūpono.
Cannabinoids a me ke kuleana o ka ECS
No ka hoʻomaopopo ʻana i ka THC vs CBD a me ke ʻano o kā lākou hopena iā mākou, pono ʻoe e hoʻomaopopo mua i ka ʻōnaehana endocannabinoid (ECS), e kōkua i ke kino e mālama i ke kaulike hana ma o kāna mau mea nui ʻekolu: nā molekala "ʻelele", a i ʻole endocannabinoids, i hana ʻia e ko mākou kino; nā mea hoʻokipa i hoʻopaʻa ʻia i kēia mau molekala; a me nā enzymes e wāwahi iā lākou.
ʻO ka ʻeha, ke koʻikoʻi, ka ʻai, ka metabolism ikehu, ka hana ʻana o ka naʻau, ka uku a me ka hoʻoikaika ʻana, ka hana hou ʻana, a me ka hiamoe he mau mea liʻiliʻi wale nō ia o nā hana o ke kino e hopena cannabinoids ma ka hana ʻana i ka ECS. He nui nā pōmaikaʻi olakino o nā cannabinoids a me ka hoʻohaʻahaʻa ʻana i ka mumū a me ka mālama ʻana i ka nausea.
He aha ka THC e hana ai
ʻO ka cannabinoid kaulana loa i loaʻa i ka lāʻau cannabis he tetrahydrocannabinol (THC). Hoʻola ia i ka mea hoʻokipa CB1, kahi mea ECS i loko o ka lolo e hoʻomalu ai i ka ʻona. Ua hōʻike ʻia ka ʻona THC e hoʻonui i ke kahe o ke koko i ka cortex prefrontal, ka ʻāpana o ka lolo i kuleana no ka hoʻoholo ʻana, ka nānā ʻana, nā mākau kaʻa, a me nā hana hoʻokō ʻē aʻe. ʻO ke ʻano maoli o nā hopena o THC i kēia mau hana ʻokoʻa mai kēlā me kēia kanaka.
Ke hoʻopaʻa ʻia ʻo THC i nā mea loaʻa CB1, hoʻoulu pū ʻo ia i nā manaʻo o ka euphoria mai ka ʻōnaehana uku o ka lolo. Hoʻoikaika ka Cannabis i ke ala uku o ka lolo, kahi e hauʻoli ai mākou, a hoʻonui i ko mākou hiki ke ʻai hou i ka wā e hiki mai ana. ʻO ka hopena o THC i ka ʻōnaehana uku o ka lolo ke kumu nui i ka hiki i ka cannabis ke hana i nā manaʻo o ka ʻona a me ka euphoria.
He aha ka CBD e hana ai
ʻO THC kahi mamao loa mai ka mea hoʻokahi wale nō i ka cannabis i loaʻa ka hopena pololei i ka hana o ka lolo. ʻO ka hoʻohālikelike kaulana loa me ka cannabidiol (CBD), ʻo ia ka lua o ka cannabinoid nui loa i loaʻa i ka lāʻau cannabis. Hoʻomaopopo pinepine ʻia ʻo CBD ma ke ʻano he non-psychoactive akā hoʻopunipuni kēia no ka mea he psychoactive kekahi mea e pili pono ana i ka hana o ka lolo. Hoʻokumu maoli ʻo CBD i nā hopena psychoactive i ka wā e launa pū ai me ka lolo a me ka ʻōnaehana nūnū waena, e like me ka mea i hōʻike ʻia he mana anti-seizure a me nā waiwai anti-anxiety.
No laila ʻoiai he psychoactive maoli ʻo CBD, ʻaʻole ia e ʻona. ʻO ia hoʻi, ʻaʻole ia e hoʻokiʻekiʻe iā ʻoe. ʻO ia no ka mea ʻino loa ʻo CBD i ka hoʻāla ʻana i ka mea hoʻokipa CB1. I ka ʻoiaʻiʻo, hōʻike nā hōʻike e hoʻopilikia maoli ia i ka hana o ka mea hoʻokipa CB1, ʻoi aku hoʻi ma ke alo o THC. Ke hana pū nei ʻo THC a me CBD e hoʻopilikia i ka hana hoʻokipa CB1, ʻoi aku ka manaʻo o nā mea hoʻohana i ka mellow, nuanced kiʻekiʻe a loaʻa ka haʻahaʻa haʻahaʻa o ka ʻike ʻana i ka paranoia i hoʻohālikelike ʻia i nā hopena i manaʻo ʻia i ka wā ʻaʻole CBD. ʻO ia no ka mea e hoʻāla ai ʻo THC i ka mea hoʻokipa CB1, ʻoiai ʻo CBD ke kāohi iā ia.
Pehea e launa pū ai ʻo CBD a me THC me kekahi
Ma ka maʻalahi, hiki i ka CBD ke pale aku i ka hōʻino ʻana i ka cognitive e pili ana me ka overexposure i THC. ʻO kahi noiʻi 2013 i paʻi ʻia ma ka Journal of Psychopharmacology i lawelawe ʻia THC i nā poʻe komo a ʻike ʻo ka poʻe i hāʻawi ʻia i ka CBD ma mua o ka hoʻokele THC i hōʻike i ka emi ʻana o ka hoʻomanaʻo episodic ma mua o nā mea maʻi i hāʻawi ʻia i kahi placebo - e hōʻike hou ana e hiki i ka CBD ke kāohi i ka cognitive THC. hemahema.
ʻO ka ʻoiaʻiʻo, ʻike ʻia kahi loiloi 2013 o kahi kokoke i 1,300 mau haʻawina i paʻi ʻia i loko o nā nūpepa ʻepekema "hiki i ka CBD ke pale aku i nā hopena maikaʻi ʻole o THC." Hōʻike ka loiloi i ka pono no ka noiʻi hou aʻe a me ka nānā ʻana i nā hopena o CBD i ka hoʻohana ʻana o THC i nā hiʻohiʻona maoli. Akā ua maopopo ka ʻikepili i loaʻa i ka CBD i ʻōlelo pinepine ʻia ma ke ʻano he antidote no ka poʻe i hoʻopau hewa ʻole i ka THC a loaʻa iā lākou iho ua kaumaha.
Hoʻopili nā Cannabinoids me nā ʻōnaehana he nui i ke kino
Hoʻopili ʻo THC a me CBD i kekahi mau pahuhopu ʻē aʻe i ke kino. ʻO CBD, no ka laʻana, he 12 mau wahi o ka hana i loko o ka lolo. A ma kahi e kaulike ai ʻo CBD i nā hopena o THC ma o ka pale ʻana i nā mea loaʻa CB1, loaʻa paha nā hopena ʻē aʻe i ka metabolism THC ma nā wahi like ʻole o ka hana.
ʻO ka hopena, ʻaʻole hiki i ka CBD ke kāohi a i ʻole ke kaulike i nā hopena o THC. Hiki iā ia ke hoʻonui pololei i nā pono olakino maikaʻi o THC. Hiki paha i ka CBD, no ka laʻana, ke hoʻonui i ka hōʻeha ʻeha o THC. ʻO THC ka mea hiki i ka anti-inflammatory a me ka neuroprotective antioxidant, ʻo ka hapa nui ma muli o kona hoʻōla ʻana i nā mea hoʻokipa CB1 i ka ʻāpana ʻeha o ka lolo.
Ua hōʻike ʻia kahi noiʻi mai 2012 e pili ana ʻo CBD me ka alpha-3 (α3) glycine receptors, kahi pahuhopu koʻikoʻi no ka hoʻomaʻamaʻa ʻana i ka ʻeha i loko o ke kuamoʻo, e kāohi i ka ʻeha mau a me ka mumū. He laʻana ia o ka mea i kapa ʻia ʻo ka entourage effect, kahi e hana pū ai nā pūhui cannabis like ʻole ma ke ʻano holoʻokoʻa e hana i kahi hopena ʻoi aku ka maikaʻi ma mua o ka ʻai ʻia ʻana.
Akā ʻaʻole maopopo loa kēia pilina. Ma kahi noiʻi ʻo Pepeluali 2019, ua ʻike nā mea noiʻi ʻo nā haʻahaʻa haʻahaʻa o CBD i hoʻonui maoli i nā hopena ʻona o THC, ʻoiai nā kiʻekiʻe kiʻekiʻe o CBD i hōʻemi i nā hopena ʻona o THC.
ʻO Terpenes a me ka hopena entourage
Hiki paha i kekahi o nā hopena ʻaoʻao kaulana loa o ka cannabis (e like me ka couch-lock) he mea liʻiliʻi loa ka pili ʻana me THC ponoʻī, akā, ʻo nā haʻawina pili o nā molekole i ʻike ʻole ʻia. Hāʻawi nā pūhui kemika i kapa ʻia ʻo terpenes i nā mea kanu cannabis i ko lākou ʻono a me nā ʻala. Loaʻa lākou i nā mea kanu he nui - e like me ka lavender, ka ʻili lāʻau, a me nā hops - a hāʻawi i ke ʻala o nā aila pono. ʻO Terpenes, ʻo ia ka pūʻulu nui loa o nā phytochemical i ʻike ʻia i ka cannabis, ua hōʻike pū ʻia he ʻāpana koʻikoʻi o ka hopena entourage. ʻAʻole wale nā terpenes e hāʻawi i ka cannabis i kahi ʻono ʻokoʻa a me ka ʻala, akā ʻike pū ʻia lākou e kākoʻo i nā molekole cannabis ʻē aʻe i ka hana ʻana i nā hopena physiological a me ka cerebral.
laina lalo
ʻO Cannabis kahi mea kanu paʻakikī me ka liʻiliʻi loa o ka noiʻi ʻana i kona hopena a me ka launa pū ʻana me ke kino o ke kanaka - a ke hoʻomaka nei mākou e aʻo i nā ʻano he nui o THC, CBD, a me nā pūhui cannabis ʻē aʻe e hana pū a launa pū me kā mākou ECS e hoʻololi i ka. ke ano o ko makou manao.
Ka manawa hoʻouna: ʻOkakopa-19-2021